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CNTN1 Antibody#43782

CNTN1 Antibody
CNTN1 Antibody
CNTN1 Antibody
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产品总价:
产品详情

产品名称CNTN1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification

应用IHC WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of total CNTN1 protein.

免疫原类型peptide

免疫原描述Synthetic peptide of human CNTN1

基因/蛋白名称CNTN1

别名F3; GP135; MYPCN

数据库入口号Swiss-Prot#: Q12860
NCBI Gene ID: 1272

UniprotQ12860

计算分子量113kd

浓度1.5mg/ml

配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500-2000
Immunohistochemistry: 1: 100-200
Gel: 6%SDS-PAGE
Lysate: 40 μg, Lane 1-5: Rat brain tissue£¬Mouse brain tissue£¬Human fetal brain tissue£¬Human cerebrum tissue£¬Human cerebella tissue lysates,
Primary antibody:CNTN1 antibody at dilution 1/550,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 10 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CNTN1 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CNTN1 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
背景
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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et al,CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in MiceInNeurotox ResOn2023 AugbyLinxuan Zhang?#?1,?Zehao Zeng et al..PMID:?37014368, , (2023),
PMID: 37014368
et al,CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and AstrocytesInAging DisOn2023 Oct 1bySong-Ji Li?1?2?3,?Min-Hui Ma et al..PMID: 37196127, , (2023),
PMID: 37196127
et al,Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes. In Brain Behav Immun on 2021 Jul by Songji Li, Wenyu Cao, et al..PMID:33737174, , (2021),
PMID: 33737174
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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